Concurrent dural and leptomeningeal metastatic carcinomatosis are very rare\nand have a poor prognosis. Here we present a woman with advanced estrogen\nreceptor (ER) positive and progesterone receptor (PR) positive breast cancer\nwho presented with leptomeningeal disease. Patient underwent multi targeted\nepigenetic therapies applied in a protocol called MTET. She continued to respond\nto the interval treatment, which consisted only of the nutraceutical\nagents. Here we discuss her case in detail and we believe that such an example\nmight be applied to other patients in this situation resulting clinical improvement\nand less toxicity.
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